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overview John J. Fung, M.D., Ph.D. is the Director of the UChicago Medicine Transplantation Institute. Prior to that, he served as Chairman of the Cleveland Clinic Health System Center for Transplantation, as well as the former Chief of the Division of Transplant Surgery at the University of Pittsburgh. With over 30 years of involvement in abdominal and cellular transplantation, he is also an accomplished immunologist. Dr. Fung received his B.A. from the Johns Hopkins University in 1975, followed by a Ph.D. in Immunology in 1980 and M.D. in 1982 from the University of Chicago. He completed his surgical residency at the University of Rochester, and a transplant surgery fellowship at the University of Pittsburgh, under the guidance of Dr. Thomas Starzl. Between 1987 and 1988, he served as Director of Histocompatibility Testing at the University of Rochester. In 1989, he joined the faculty at the University of Pittsburgh and held the tenured position as the inaugural Thomas E. Starzl Professor in Surgery. He joined the Cleveland Clinic in 2004 as the Chairman of the Department of General Surgery and Professor of Surgery at the Lerner College of Medicine at Case Western University. He also served as the Medical Director of Allogen Laboratory, one of the largest histocompatibility laboratories in the United States and oversaw transplantation services at five Cleveland Clinic facilities globally. In 2016, he was recruited to serve as the Director of the newly created University of Chicago Medicine Transplantation Institute. Dr. Fung is a member of numerous scientific and surgical societies and served as President of the International Liver Transplantation Society from 1997-1999. He is currently Secretary of the Transplantation Society. He has published over 1,000 articles and book chapters and serves on the editorial board for several medical journals. He is the immediate past Editor-in-Chief for Liver Transplantation, the highest impact factor specialty transplant journal. His principal research interests are in transplantation immunology, immunosuppressive therapies, and liver related immunology. In addition, he has received numerous prestigious lay and professional awards. His research interests are in transplant immunology, liver immunity, immnosuppression, and outcomes analysis. Dr. Fung is active in community affairs and has been a member of the Board of Directors at the Americans for Medical Progress and the Gift of Hope Organ Procurement Organization. He received an honorable discharge from the United States Army Reserve Medical Corps with the rank of Lieutenant Colonel. He and his wife, Beth have four children: Justin, Lauren, Brendan and Shannon.
One or more keywords matched the following items that are connected to Fung, John
Item TypeName
Concept Acute Disease
Concept Brain Diseases
Concept Autoimmune Diseases
Concept Bile Duct Diseases
Concept Biliary Tract Diseases
Concept Gastrointestinal Diseases
Concept Cardiovascular Diseases
Concept Graft vs Host Disease
Concept Coronary Disease
Concept Communicable Diseases
Concept Coronary Artery Disease
Concept Chronic Disease
Concept Kidney Diseases
Concept Heart Diseases
Concept Hematologic Diseases
Concept Hospitals, Pediatric
Concept Intestinal Diseases
Concept Iatrogenic Disease
Concept Liver Diseases, Alcoholic
Concept Nervous System Diseases
Concept Lymphatic Diseases
Concept Hodgkin Disease
Concept Immune Complex Diseases
Concept Caroli Disease
Concept Tooth Diseases
Concept Disease Transmission, Infectious
Concept Vascular Diseases
Concept Inflammatory Bowel Diseases
Concept Vestibular Diseases
Concept Disease Progression
Concept End Stage Liver Disease
Concept General Surgery
Concept Arterial Occlusive Diseases
Concept Disease Models, Animal
Concept Liver Diseases
Concept Virus Diseases
Concept Disease-Free Survival
Concept Genetic Predisposition to Disease
Academic Article Alcoholic liver disease and transplantation.
Academic Article Conversion from tacrolimus to cyclosporine--a based immunosuppression following liver transplantation.
Academic Article Human herpesvirus-6 in liver transplant recipients: role in pathogenesis of fungal infections, neurologic complications, and outcome.
Academic Article Immune complex disease in immunosuppressed rat recipients of hamster liver xenografts.
Academic Article Small bowel transplantation: current progress and clinical application.
Academic Article Split-liver transplantation: a comparison of ex vivo and in situ techniques.
Academic Article FK 506 versus cyclosporine in pediatric liver transplantation.
Academic Article Resolution of severe pyoderma gangrenosum in a patient with streaking leukocyte factor disease after treatment with tacrolimus (FK 506).
Academic Article Disease gravity and urgency of need as guidelines for liver allocation.
Academic Article Pathophysiologic observations and histopathologic recognition of the portal hyperperfusion or small-for-size syndrome.
Academic Article Clinical intestinal transplantation: focus on complications.
Academic Article A critical role of TRAIL expressed on cotransplanted hepatic stellate cells in prevention of islet allograft rejection.
Academic Article De novo sirolimus and reduced-dose tacrolimus versus standard-dose tacrolimus after liver transplantation: the 2000-2003 phase II prospective randomized trial.
Academic Article Cardiac changes at autopsy in adult liver transplant recipients under tacrolimus.
Academic Article Acute pancreatitis after liver transplantation: incidence and contributing factors.
Academic Article Combined heart and liver transplantation: the Cleveland Clinic experience.
Academic Article Pharmacokinetics of mycophenolic acid after mycophenolate mofetil administration in liver transplant patients treated with tacrolimus.
Academic Article Bronchiolitis obliterans organizing pneumonia in a BMT patient receiving FK506.
Academic Article Primary tacrolimus (FK506) therapy and the long-term risk of post-transplant lymphoproliferative disease in pediatric liver transplant recipients.
Academic Article Liver transplantation for nonalcoholic steatohepatitis in young patients.
Academic Article Split liver transplantation using Hemiliver graft in the MELD era: a single center experience in the United States.
Academic Article Intestinal transplantation in composite visceral grafts or alone.
Academic Article Prioritization and organ distribution for liver transplantation.
Academic Article Adverse effects associated with the use of FK 506.
Academic Article FK 506 used as rescue therapy for human liver allograft recipients.
Academic Article Clinical intestinal transplantation.
Academic Article The Pittsburgh randomized trial of tacrolimus compared to cyclosporine for hepatic transplantation.
Academic Article The induction of pseudo-graft-versus-host disease following syngeneic bone marrow transplantation using FK 506.
Academic Article Hyperbaric oxygen therapy for hepatic artery thrombosis after liver transplantation in children.
Academic Article Allogeneic hematolymphoid microchimerism and prevention of autoimmune disease in the rat. A relationship between allo- and autoimmunity.
Academic Article Time to detection of cytomegalovirus (CMV) DNA in blood leukocytes is a predictor for the development of CMV disease in CMV-seronegative recipients of allografts from CMV-seropositive donors following liver transplantation.
Academic Article A clinical trial combining donor bone marrow infusion and heart transplantation: intermediate-term results.
Academic Article The two-way paradigm of transplantation immunology.
Academic Article [Clinical experience with FK 506].
Academic Article Preservation injury and acute rejection of rat intestinal grafts: protection afforded by pyruvate.
Academic Article Real-time monitoring of acute liver-allograft rejection using the Banff schema.
Academic Article Chronic liver allograft rejection in a population treated primarily with tacrolimus as baseline immunosuppression: long-term follow-up and evaluation of features for histopathological staging.
Academic Article Liver transplantation for hepatocellular carcinoma: a proposal of a prognostic scoring system.
Academic Article Prevention of sensitization and hyperacute rejection in liver and heart xenografts by FK 506 plus donor antigens.
Academic Article Hepatic artery angioplasty after liver transplantation: experience in 21 allografts.
Academic Article Thrombotic and nonthrombotic hepatic artery complications in adults and children following primary liver transplantation with long-term follow-up in 1000 consecutive patients.
Academic Article A randomized trial of inhaled cyclosporine in lung-transplant recipients.
Academic Article The effect of cyclosporine, rapamycin and FK 506 the survival following allogeneic bone marrow transplantation.
Academic Article Adenosine Increases Hepatic Artery Flow in Liver Transplant Recipients: A Pilot Study.
Academic Article Daily serum interleukin-6 monitoring in multiple organ transplantation with or without liver allografts.
Academic Article Tobacco use following liver transplantation for alcoholic liver disease: an underestimated problem.
Academic Article Impact of De Novo and Preexisting Inflammatory Bowel Disease on the Outcome of Orthotopic Liver Transplantation.
Academic Article Xenogeneic humoral graft-Vs-host disease following hamster-to-Rat bone marrow transplantation.
Academic Article Hepatic transplantation during pregnancy and the puerperium.
Academic Article Caroli's disease and orthotopic liver transplantation.
Academic Article Explanation for loss of the HLA matching effect.
Academic Article Chronic rejection. A general overview of histopathology and pathophysiology with emphasis on liver, heart and intestinal allografts.
Academic Article Neurologic complications of FK 506.
Academic Article Increased bile duct complications and/or chronic rejection in crossmatch positive human liver allografts.
Academic Article An analysis of pretransplantation variables associated with long-term allograft outcome in pediatric liver transplant recipients receiving primary tacrolimus (FK506) therapy.
Academic Article Intestinal transplantation: a coming of age.
Academic Article The liver transplant waiting list--a single-center analysis.
Academic Article Orthotopic liver transplantation for patients with hepatitis B virus-related liver disease.
Academic Article The absence of chronic rejection in pediatric primary liver transplant patients who are maintained on tacrolimus-based immunosuppression: a long-term analysis.
Academic Article Cytokine profile in graft-versus-host disease after small bowel transplantation.
Academic Article Administration of CTLA4-Ig enhances the incidence of hamster-to-rat xenogeneic bone marrow engraftment and alters the presentation of graft-vs-host disease.
Academic Article Reversal of acute cellular rejection after renal transplantation with Campath-1H.
Academic Article Outcomes in 139 cases of biliary tract reconstructions from a transplant surgery center.
Academic Article Role of Doppler Sonography in Early Detection of Splenic Steal Syndrome.
Academic Article Splenic artery embolization for the treatment of refractory ascites after liver transplantation.
Academic Article Dental health status of liver transplant candidates.
Academic Article Evolution of hepatitis B virus liver disease after hepatic replacement. Practical and theoretical considerations.
Academic Article Outcome after steroid withdrawal in pediatric renal transplant patients receiving tacrolimus-based immunosuppression.
Academic Article Analysis of chronic rejection and obliterative arteriopathy. Possible contributions of donor antigen-presenting cells and lymphatic disruption.
Academic Article FK 506 rescue in chronic graft-versus-host-disease after bone marrow transplantation.
Academic Article Prolonged prevention of acute graft-versus-host disease after allogeneic bone marrow transplantation by donor pretreatment using FK 506.
Academic Article Treatment of Cogan's syndrome with FK 506: a case report.
Academic Article Posttransplant lymphoproliferative disorders in adult and pediatric renal transplant patients receiving tacrolimus-based immunosuppression.
Academic Article Adenosine restores the hepatic artery buffer response and improves survival in a porcine model of small-for-size syndrome.
Academic Article Liver transplantation for alcoholic liver disease, viral hepatitis, and hepatic neoplasms.
Academic Article Perioperative donor bone marrow infusion in recipients of organ allografts.
Academic Article Progression of liver fibrosis in patients with chronic hepatitis C after orthotopic liver transplantation.
Academic Article Relationship between the diagnosis, preoperative evaluation, and prognosis after orthotopic liver transplantation.
Academic Article Hamster-to-rat bone marrow xenotransplantation and humoral graft vs. host disease.
Academic Article Radiologic-histological correlation of hepatocellular carcinoma treated via pre-liver transplant locoregional therapies.
Academic Article Role of MHC class I and CD8(+) T cells in the pathogenesis of chronic rejection.
Academic Article Hepatitis G virus coinfection in hepatitis C virus-infected liver transplant recipients.
Academic Article The liver allograft, chronic (ductopenic) rejection, and microchimerism: what can they teach us?
Academic Article Clinical intestinal transplantation: new perspectives and immunologic considerations.
Academic Article Combined blockade of CD28/B7 and CD40/CD40L costimulatory pathways prevents the onset of chronic rejection.
Academic Article Perioperative and oncologic outcomes of minimally invasive liver resection for colorectal metastases: A case-control study of 130 patients.
Academic Article Pregnancy after liver transplantation with tacrolimus immunosuppression: a single center's experience update at 13 years.
Academic Article Blockade of the CD28/B7 and CD40/CD40L costimulatory pathways does not ameliorate chronic rejection in a mouse aortic allograft model of direct antigen presentation.
Academic Article Rejection triggers liver transplant tolerance: Involvement of mesenchyme-mediated immune control mechanisms in mice.
Academic Article Pretransplant survival is shorter in HIV-positive than HIV-negative subjects with end-stage liver disease.
Academic Article Causes of retransplantation after primary liver transplantation in 4000 consecutive patients: 2 to 19 years follow-up.
Academic Article Replicative senescence of biliary epithelial cells precedes bile duct loss in chronic liver allograft rejection: increased expression of p21(WAF1/Cip1) as a disease marker and the influence of immunosuppressive drugs.
Academic Article Transjugular intrahepatic portosystemic shunt in patients with end-stage liver disease: results in 85 patients.
Academic Article Two-year experience with FK 506 in pediatric patients.
Academic Article Intestinal transplantation in humans under FK 506.
Academic Article Incidence and risk factors associated with the development of cytomegalovirus disease after intestinal transplantation.
Academic Article Spindle cell tumor of the portal vein.
Academic Article Variable chimerism, graft-versus-host disease, and tolerance after different kinds of cell and whole organ transplantation from Lewis to brown Norway rats.
Academic Article Between Scylla and Charybdis.
Academic Article Hemodynamic effects of inhaled nitric oxide in four patients with severe liver disease and pulmonary hypertension.
Academic Article Outcome of liver transplantation using donors 60 to 79 years of age.
Academic Article Current status of intestinal transplantation in children.
Academic Article Orthotopic liver transplantation in high-risk patients: risk factors associated with mortality and infectious morbidity.
Academic Article Structural integrity and identification of causes of liver allograft dysfunction occurring more than 5 years after transplantation.
Academic Article Liver transplantation for alcoholic cirrhosis: long term follow-up and impact of disease recurrence.
Academic Article The protection from humoral rejection given by a liver xenograft is species-specific and non-MHC restricted.
Academic Article Alcohol consumption patterns and predictors of use following liver transplantation for alcoholic liver disease.
Academic Article Sirolimus for rescue and primary immunosuppression in transplanted children receiving tacrolimus.
Academic Article Management of posttransplant lymphoproliferative disease in pediatric liver transplant recipients receiving primary tacrolimus (FK506) therapy.
Academic Article Pediatric renal transplantation under tacrolimus-based immunosuppression.
Academic Article Impact of anti-hepatitis Bc-positive grafts on the outcome of liver transplantation for HBV-related cirrhosis.
Academic Article Autologous Reconstruction and Visceral Transplantation for Management of Patients With Gut Failure After Bariatric Surgery: 20 Years of Experience.
Academic Article Complement mediated hepatocytes injury in a model of autoantibody induced hepatitis.
Academic Article Sequential infiltration of class I and class II specific alloreactive T cells in human cardiac allografts.
Academic Article Conversion of liver allograft recipients from cyclosporine to FK506 immunosuppressive therapy--a clinicopathologic study of 96 patients.
Academic Article A new xenogeneic radiation chimera (hamster-to-rat).
Academic Article Central nervous system lesions in liver transplant recipients: prospective assessment of indications for biopsy and implications for management.
Academic Article Deep hypothermia with circulatory arrest to aid in the management of suprahepatic vena cava stenosis after liver transplantation.
Academic Article The incidence, timing, and management of biliary tract complications after orthotopic liver transplantation.
Academic Article Cruveilhier-Baumgarten disease in a patient with Turner syndrome: case report of a rare indication for liver transplantation.
Academic Article Urgent revascularization of liver allografts after early hepatic artery thrombosis.
Academic Article Experimental animal model of graft-versus-host disease (GVHD) after small-bowel transplantation: characteristics of the model and application to developing treatment strategies.
Academic Article Attenuation of aortic graft arteriosclerosis by systemic administration of Allotrap peptide RDP58.
Academic Article Effect of coadministered lopinavir and ritonavir (Kaletra) on tacrolimus blood concentration in liver transplantation patients.
Academic Article Recurrent hepatitis C in liver allografts: prospective assessment of diagnostic accuracy, identification of pitfalls, and observations about pathogenesis.
Academic Article Complement anaphylatoxin receptors C3aR and C5aR are required in the pathogenesis of experimental autoimmune uveitis.
Academic Article Myeloid suppressor cells induced by retinal pigment epithelial cells inhibit autoreactive T-cell responses that lead to experimental autoimmune uveitis.
Academic Article Liver transplantation for fatty liver disease.
Academic Article Natural history of Epstein-Barr viral load in peripheral blood of pediatric liver transplant recipients during treatment for posttransplant lymphoproliferative disorder.
Academic Article Loco-regional therapy in patients with Milan Criteria-compliant hepatocellular carcinoma and short waitlist time to transplant: an outcome analysis.
Academic Article Effect of hepatic dysfunction and T tube clamping on FK 506 pharmacokinetics and trough concentrations.
Academic Article The pitfall of the cystic duct biliary anastomosis in right lobe living donor liver transplantation.
Academic Article The patient with chronic hepatitis C.
Academic Article Use of prostaglandin E1 in crossmatch-negative liver transplant recipients treated with FK 506.
Academic Article A Structured Educational Curriculum Including Online Training Positively Impacts American Board of Surgery In-Training Examination Scores.
Academic Article Prevention of chronic rejection in mouse aortic allografts by combined treatment with CTLA4-Ig and anti-CD40 ligand monoclonal antibody.
Academic Article Porcine partial liver transplantation: a novel model of the "small-for-size" liver graft.
Academic Article Effect of liver transplantation on inflammatory bowel disease in patients with primary sclerosing cholangitis.
Academic Article Immune modulation in organ allograft recipients by single or multiple donor bone marrow infusions.
Academic Article Robotic versus laparoscopic resection of liver tumours.
Academic Article Using livers from donation after cardiac death donors--a proposal to protect the true Achilles heel.
Academic Article FK 506 reverses acute graft-versus-host disease after allogeneic bone marrow transplantation in rats.
Academic Article Pediatric liver transplantation in 808 consecutive children: 20-years experience from a single center.
Academic Article Prevention of graft-versus-host disease following allogeneic bone marrow transplantation in rats using FK506.
Academic Article Prognostic role of plasma vascular endothelial growth factor in patients with hepatocellular carcinoma undergoing liver transplantation.
Academic Article Lymphoma resembling Hodgkin disease after posttransplant lymphoproliferative disorder in a liver transplant recipient.
Academic Article Use of FK 506 in pediatric patients.
Academic Article Portacaval shunt causes apoptosis and liver atrophy in rats despite increases in endogenous levels of major hepatic growth factors.
Academic Article Conversion from cyclosporine to FK 506 in liver allograft recipients with cyclosporine-related complications.
Academic Article Predicting the discharge status after liver transplantation at a single center: a new approach for a new era.
Academic Article Experiences relating to management of biliary tract complications following liver transplantation in 96 cases.
Academic Article Posttransplant diabetes in pediatric recipients on tacrolimus.
Academic Article Infectious complications after human small bowel transplantation.
Academic Article Infections with FK 506 immunosuppression: preliminary results with primary therapy.
Academic Article Effect of tacrolimus and splenectomy on engraftment and GVHD after bone marrow xenotransplantation in the reciprocal hamster to rat animal models.
Academic Article Duct-to-duct biliary reconstruction in patients with primary sclerosing cholangitis undergoing liver transplantation.
Academic Article Minimal criteria for placement of adults on the liver transplant waiting list: a report of a national conference organized by the American Society of Transplant Physicians and the American Association for the Study of Liver Diseases.
Academic Article Elevated catecholamines and hepatic artery vasospasm in porcine small-for-size liver graft.
Academic Article Orthotopic liver transplantation in patients with human immunodeficiency virus and end-stage liver disease.
Academic Article Liver transplantation for acute liver failure: outcome analysis.
Academic Article The immunolymphatic theory of chronic rejection.
Academic Article Liver transplantation under cyclosporine: a decade of experience.
Academic Article Almost total absence of chronic rejection in primary pediatric liver transplantation under tacrolimus.
Academic Article The many faces of multivisceral transplantation.
Academic Article Three years clinical experience with intestinal transplantation.
Academic Article Pediatric liver transplantation. A single center experience spanning 20 years.
Academic Article C-C Chemokine Receptor Type 2-Dependent Migration of Myeloid-Derived Suppressor Cells in Protection of Islet Transplants.
Academic Article Role of donor hemodynamic trajectory in determining graft survival in liver transplantation from donation after circulatory death donors.
Academic Article Hemophilia Liver Transplantation Observational Study.
Academic Article Donor IFNL4 Genotype Is Associated with Early Post-Transplant Fibrosis in Recipients with Hepatitis C.
Academic Article Limitations of current liver transplant immunosuppressive regimens: renal considerations.
Academic Article Liver transplantation in patients with incidental hepatocellular carcinoma/cholangiocarcinoma and intrahepatic cholangiocarcinoma: a single-center experience.
Academic Article Recipient But Not Donor Adiponectin Polymorphisms Are Associated With Early Posttransplant Hepatic Steatosis in Patients Transplanted for Non-Nonalcoholic Fatty Liver Disease Indications.
Academic Article Association Between Renal Dysfunction and Major Adverse Cardiac Events After Liver Transplantation: Evidence from an International Randomized Trial of Everolimus-Based Immunosuppression.
Academic Article Lipid metabolism and functional assessment of discarded human livers with steatosis undergoing 24 hours of normothermic machine perfusion.
Academic Article International Liver Transplantation Society Consensus Statement on Immunosuppression in Liver Transplant Recipients.
Award or Honor Receipt National Kidney Foundation Western Pennsylvania Annual Gift of Life Award
Award or Honor Receipt Achievement in Liver Transplantation Award
Award or Honor Receipt Thomas Starzl State-of-the-Art Liver Transplant Lecturer
Award or Honor Receipt James Ted Engle Pediatric Lecturer
Academic Article A Comparison of the Initial Cost Associated With Resection Versus Laparoscopic Radiofrequency Ablation of Small Solitary Colorectal Liver Metastasis.
Academic Article CD6 Receptor Regulates Intestinal Ischemia/Reperfusion-induced Injury by Modulating Natural IgM-producing B1a Cell Self-renewal.
Academic Article Medically Necessary, Time-Sensitive Procedures: Scoring System to Ethically and Efficiently Manage Resource Scarcity and Provider Risk During the COVID-19 Pandemic.
Academic Article Liver transplantation for alcoholic hepatitis in the United States: Excellent outcomes with profound temporal and geographic variation in frequency.
Concept Non-alcoholic Fatty Liver Disease
Academic Article Comparing High- and Low-Model for End-Stage Liver Disease Living-Donor Liver Transplantation to Determine Clinical Efficacy: A Systematic Review and Meta-Analysis (CHALICE Study).
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